Scientist - Metabolism & Immunometabolism


Basel Area - Allschwil, BL, CH



About Idorsia Pharmaceuticals Ltd

Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients.

In order to achieve this, we will develop Idorsia into one of Europe’s leading biopharmaceutical company, with a strong scientific core.

Headquartered in Switzerland - a European biotech hub - Idorsia is specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet – the ideal constellation to bringing R&D efforts to business success.

Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 600 highly qualified specialists dedicated to realizing our ambitious targets.


Job Responsibilities


The scientist will be responsible to expand the expertise in cellular metabolism to validate targets and analyze inhibitors in immunology and other therapeutic areas of interest to Idorsia (CNS, CV/fibrosis, oncology). This will include the development of enzymatic and cell-based assays, utilize metabolomic data and participate in compound profiling. You will be part of a drug discovery group with a strong focus on metabolic processes whose members are working on the discovery and preclinical development focusing on inhibitors and modulators of bacterial and human enzymes following an interdisciplinary approach, combining various in vitro biochemical and cellular assays.


In a first phase, you will collaborate with project teams with an immunology focus. Later, you will also drive the exploration of the concept into alternative disease areas and be part of cross-functional projects teams working on individual targets.


The scientist in metabolism will also be responsible for:


  • Driving the exploration and validation of novel drug targets
  • Prioritizing work according to project goals and take responsibility for the timely delivery of objectives
  • Keeping up to date with scientific knowledge in general and project-related areas of immunometabolism
  • Continuous evaluation, validation and implementation of new tools and methodologies
  • Collaboratively working within the team and communicating effectively and actively
  • Documenting, reporting and summarizing data for presentation to different audiences.
  • Publishing, presenting and discussing scientific results at international meetings
  • Supervising the activities of laboratory technicians or research associates


Candidate's Requirement


You are an enthusiastic, open-minded scientist interested to solve challenging scientific questions and a proactive communicator with very good organizational and planning skills and the ability to maintain good and consistent working relationships with the members of a multidisciplinary team. You are a results-oriented professional with interests in accelerating drug discovery through innovative experimental approaches and collaborations. Applicants should accompany their expression of interest with a detailed CV including their research interests, technological skills, peer reviewed publications and the contact information from at least two referees.


  • University diploma and PhD in either biochemistry or cell biology.
  • Professional or postdoctoral experience in a research environment with relevant publications in peer reviewed scientific journals
  • Previous advanced research experience in cellular metabolism including the analysis of metabolomic data
  • A strong background in applying biochemical or biophysical methods to study ligand-protein interactions will be advantageous
  • Industry experience would be a valuable asset.
  • Proficient in the English language. German and/or French would be an advantage.
  • Proven communication skills in a multicultural and multidisciplinary environment


What Idorsia offers


  • Exciting opportunities for development and professional growth within our dynamic organization
  • A collaborative and solution-oriented environment where you can make a difference
  • An innovative and open culture in a truly multicultural environment
  • A competitive salary and generous social benefits


Work Location: Allschwil

Country: Switzerland

Business Area: Research & Development

Schedule: Fulltime

Job Type: Permanent

Job ID: 1164


If you are interested, please click on apply now.

Please be informed that if you are selected for this position, your employment will be subject to a pre-employment background screening process, of which you would be informed in greater detail in due course.

Please note Idorsia operates a strictly-controlled list of preferred recruitment partners. For those partners who have no valid, signed Master Service Agreement in place with Idorsia all unsolicited resumes, CVs, anonymous profiles, or any other candidate details submitted through our website or to personal e-mail accounts of employees of Idorsia Pharmaceuticals (including any of its subsidiaries, affiliates or related companies) are considered the property of Idorsia Pharmaceuticals and are not subject to payment of any form of introduction, placement or referral fees.

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